acute/chronic pain relief: is althaea officinalis essential oil effective?
نویسندگان
چکیده
conclusions eoao showed an analgesic effect that may involve both the central and peripheral nervous systems. background the althaea officinalis (marshmallow) plant is traditionally used to treat skin burns and constipation and to reduce inflammation. objectives the aim of this study was to evaluate the acute and chronic analgesic effects of the essential oil of althaea officinalis leaves (eoao) in adult male mice. materials and methods this experimental study used thirty-six adult male mice, which were randomly divided into six groups: a control, three groups treated with eoao (18, 38, or 80 mg/kg, i.p.), a morphine group (1 mg/kg, i.p.), and a group treated with a combination of naloxone (1 mg/kg, i.p.) and 80 mg/kg eoao. the analgesic effects of eoao were evaluated by writhing, tail-flick, and formalin tests. the essential oil of the plant was prepared by the steady distillation method and its composition was analyzed by gc/ms. results significant antinociceptive effects were noted with doses of 38 and 80 mg/kg eoao in the chronic phase response of the formalin test (p < 0.05 versus control). doses of 38 and 80 mg/kg eoao had a significant analgesic effect in the writhing test (p < 0.05 and p < 0.01, respectively, versus control). the 80 mg/kg dose of eoao caused an enhancement in reaction time in the tail-flick test (p < 0.01 versus control).
منابع مشابه
Anti-Inflammatory Effects of Rosmarinus officinalis Essential Oil in Mice
Essential oils are plant secondary metabolites possessing various pharmacological properties, primarily anti-oxidative, antimicrobial or immunomodulative, but they can exhibit toxic and allergic effects as well. The aim of this study was to compare the effects of Rosmarinus officinalis essential oil dietary administration in carrageenan paw oedema and trinitrobenzene sulfonic acid (TNBS) coliti...
متن کاملToxicity of Rosmarinus Officinalis Essential Oil against Irradiated Tribolium Castaneum
Management of stored-product insect using gamma radiation could be enhanced by other feasible control methods such as essential oils as potent alternatives to chemical insecticides. In this study, the efficiency of sub-lethal doses of essential oils from Rosmarinus officinalis L. combined with gamma radiation was verified to assess their enhanced toxicity against the adults of Tribolium castane...
متن کاملRosmarinus officinalis essential oil: antiproliferative, antioxidant and antibacterial activities
The aim of this work was to investigate and compare the antiproliferative, antioxidant and antibacterial activities of Rosmarinus officinalis essential oil, native to Pakistan. The essential oil content from the leaves of R. officinalis was 0.93 g 100g(-1). The GC and GC-MS analysis revealed that the major components determined in R. officinalis essential oil were 1,8-cineol (38.5%), camphor (1...
متن کاملComparing Essential Oil Composition and Essential Oil Yield of Rosemarinus Officinalis and Lavandula Angustifolia before and Full Flowering Stages
The chemical composition of essential oils and essential oil yield obtained from Rosemarinus officinalis (family Lamiaceae) and Lavandula angustifolia (family Lamiaceae) were determined in two harvesting times. Their essential oil was determined by hydro-distillation, and analysed by GC/MS. The results showed that harvesting time had significant effects on the oil content and compositions in bo...
متن کاملInduction of Phenolic Compounds is Affected by Boron Supply in Marshmallow (Althaea officinalis L. ) Cells
Boron (B) is a non-metal micronutrient which is essential for plants growth and development. Formation of boron complex with cell wall matrix and phenolic compounds is a definite influence of boron in physiological process. It has been suggested that B-toxicity and deficiency may induce excess production of reactive oxygen species thereby promote defense responses by antioxidant enzymes or non-...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
avicenna journal of neuro psycho physiologyجلد ۲، شماره ۴، صفحات ۰-۰
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023